Achondroplasia

=Achondroplasia: The Essence of Dwarfism=

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 * a type of autosomal dominant genetic disorder that is a common cause of dwarfism.
 *  Achondroplastic dwarfs have short stature, with an average adult height of 131 cm (4 feet, 3-1/2 inches) for males and 123 cm (4 feet, 1/2 inch) for females.
 *  The prevalence is approximately 1 in 25,000.
 *  Dwarfism is a result of autosomal dominant mutation in the fibroblast growth factor receptor gene 3, which causes an abnormality of cartilage formation.
 * A person with achondroplasia has a 50% chance of passing on the gene to their offspring, meaning that there will be a 50% chance that each child will have achondroplasia. Since two copies (Homozygous) are fatal, if two people with achondroplasia have a child, there is a 25% chance of the child dying shortly after birth, a 50% chance the child will have achondroplasia, and a 25% chance the child will have an average phenotype.
 * There is no treatment for Achondroplasia.